Calcium Antagonists in Aneurysmal Subarachnoid Hemorrhage

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Calcium antagonists for aneurysmal subarachnoid haemorrhage.

BACKGROUND Secondary ischaemia is a frequent cause of poor outcome in patients with subarachnoid haemorrhage (SAH). Its pathogenesis has been incompletely elucidated, but vasospasm probably is a contributing factor. Experimental studies have suggested that calcium antagonists can prevent or reverse vasospasm and have neuroprotective properties. OBJECTIVES To determine whether calcium antagoni...

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Aneurysmal subarachnoid hemorrhage.

From the Departments of Neurology ( J.I.S.), Radiology (R.W.T.), and Neurosurgery (W.R.S.), University Hospitals of Cleveland, Case Western Reserve University, Cleveland. Address reprint requests to Dr. Suarez at the Department of Neurology, Neurosciences Critical Care and Cerebrovascular Center, University Hospitals of Cleveland, Case Western Reserve University, 11100 Euclid Ave., Cleveland, O...

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Aneurysmal Subarachnoid Hemorrhage

Aneurysmal subarachnoid hemorrhage (SAH) is a worldwide health burden with high fatality and permanent disability rates. The overall prognosis depends on the volume of the initial bleed, rebleeding, and degree of delayed cerebral ischemia (DCI). Cardiac manifestations and neurogenic pulmonary edema indicate the severity of SAH. The International Subarachnoid Aneurysm Trial (ISAT) reported a fav...

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Aneurysmal Subarachnoid Hemorrhage

Background and Purpose: Aneurysmal subarachnoid hemorrhage is a serious disease despite recent improvements in medical and surgical treatment. Hence, identification of modifiable risk factors for subarachnoid hemorrhage is important. Methods: We compared the smoking and drinking habits of 278 consecutive patients with aneurysmal subarachnoid hemorrhage, aged 15-60 years (145 men and 133 women) ...

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Copeptin in aneurysmal subarachnoid hemorrhage

Copeptin is a peptide derived from pre-provasospression along with arginine vasospressin. In the setting of aneurysmal subarachnoid hemorrhage (SAH), elevated serum copeptin levels correlate with vasospasm, inpatient mortality, mortality at 1 year, and poor functional outcome at 1 year. The potential role of serum copeptin levels in the management of patients with aneurysmal SAH is promising an...

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ژورنال

عنوان ژورنال: Stroke

سال: 2005

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.0000177502.96190.71